A lot of people have a very diverse outlook on barefoot running. I'm not providing my own opinion at this point, but rather one random musing. Really, there have been very, very few legitimate scientific, peer reviewed studies on this particular topic, so it'd be very, very unprofessional to give expert opinion at this point. I'll probably end up giving it any at some point.
The calcaneus (heel bone) has a special are called the neutral triangle. It's were the trabeculae (bone scaffold) meet at a particular angle such that they transfer forces beautifully. From the heel forward. Further more, equinus, or the condition of walking on your tip toes all the time, leads to a whole cohort of problems later in life. It's something to consider, by no means definitive.
I do, however, fully agree with the ideas of Cody Lundin. He advocates a barefoot approach to survival and hiking in general. I understand where he's coming from, by going barefoot he's forced to go slow. I like the idea. I personally wouldn't like to walk through the jungle, leishmaniasis and all, but I understand it.
Check him out here